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UCSF ChimeraX

Next-generation molecular visualization.

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Overview

UCSF ChimeraX is the next-generation molecular visualization program from the RBVI lab at UC San Francisco, succeeding the widely used UCSF Chimera. It is designed for the visualization and analysis of molecular structures, density maps, 3D microscopy data, and sequence alignments. It features high-performance rendering and a modern, extensible software framework.

✨ Key Features

  • High-quality molecular graphics and rendering
  • Analysis of molecular structures and properties
  • Visualization of volumetric data (cryo-EM maps, etc.)
  • Sequence alignment viewing
  • Structure building and editing
  • Extensible via Python API and toolshed

🎯 Key Differentiators

  • Excellent performance with very large datasets (e.g., large cryo-EM maps).
  • Modern user interface and command-line integration.
  • Free for non-commercial use and actively developed.

Unique Value: Provides cutting-edge, high-performance visualization and analysis of complex molecular and microscopy data, free for academic use.

🎯 Use Cases (5)

Structural biology research Drug design and discovery Cryo-electron microscopy data analysis Creating publication-quality molecular images and movies Educational demonstrations of molecular structures

βœ… Best For

  • Extensively used in academia for structural biology research and education.
  • Utilized by pharmaceutical companies for visualizing protein-ligand interactions.

πŸ’‘ Check With Vendor

Verify these considerations match your specific requirements:

  • NGS data analysis
  • Mass spectrometry data processing
  • Laboratory Information Management (LIMS)

πŸ† Alternatives

PyMOL Discovery Studio MOE (Molecular Operating Environment)

Offers superior performance on large datasets and a more modern architecture compared to its predecessor (Chimera) and some commercial alternatives.

πŸ’» Platforms

Desktop

βœ… Offline Mode Available

πŸ”Œ Integrations

AlphaFold Database PDB and EMDB databases Python scripting

πŸ›Ÿ Support Options

  • βœ“ Email Support
  • βœ“ Dedicated Support (None tier)

πŸ’° Pricing

Contact for pricing
Free Tier Available

Free tier: Free for academic, government, non-profit, and personal use.

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