Mascot
The standard in protein identification using mass spectrometry data.
Overview
Mascot, developed by Matrix Science, is one of the most widely used and respected search engines for protein identification in proteomics. It correlates tandem mass spectrometry (MS/MS) data against sequence databases to identify the proteins present in a sample. It can be accessed via a web interface or integrated into other data analysis platforms.
✨ Key Features
- Protein identification by MS/MS database searching
- Support for a wide range of data formats and search parameters
- Probabilistic scoring (MOWSE)
- Quantification support (SILAC, TMT, etc.)
- Error tolerant searching for modifications and mutations
- Spectral library searching
🎯 Key Differentiators
- Highly trusted, statistically rigorous scoring.
- Comprehensive support for modifications and enzyme specificities.
- Robust and reliable performance.
Unique Value: Provides highly reliable and statistically validated protein identifications from tandem mass spectrometry data, serving as a cornerstone of proteomics research.
🎯 Use Cases (3)
✅ Best For
- A benchmark tool for protein identification for over two decades.
- Extensively cited in scientific literature.
💡 Check With Vendor
Verify these considerations match your specific requirements:
- De novo sequencing
- Complete quantitative analysis (often requires other software)
- Data acquisition
🏆 Alternatives
Often considered more statistically transparent and rigorous than other search engines, and serves as a trusted benchmark for results.
💻 Platforms
✅ Offline Mode Available
🔌 Integrations
🛟 Support Options
- ✓ Email Support
- ✓ Phone Support
- ✓ Dedicated Support (In-house Server License tier)
💰 Pricing
✓ 14-day free trial
Free tier: Free public server for searching limited datasets.
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